There are many studies being done to look at whether certain vitamin and mineral supplements and combinations of supplements may help prevent age-related macular degeneration (AMD) or delay vision loss in people who already have it.
For example, the Age-Related Eye Disease Study (AREDS) and AREDS2 were two major research studies done by the
U.S. National Eye Institute. AREDS2 found that supplementing your diet with high
levels of vitamins C, E, lutein, and zeaxanthin, which are all
antioxidants, and the minerals zinc and copper may help slow the
progress of advanced
age-related macular degeneration (AMD) and delay
vision loss if you already have moderate or severe AMD.
There is no evidence that the supplements are helpful if you do
not have AMD or only have a mild form of the disease.footnote 1
In a study of male doctors who didn't have AMD, researchers found that taking vitamins E and C for up to 8 years, either alone or in combination, was not likely to affect whether or not a person got early AMD. This finding is consistent with other studies that looked at preventing AMD by using vitamins.footnote 2
If you're interested in taking a vitamin or mineral supplement, talk with your doctor about the risks. For example:
CitationsAmerican Academy of Ophthalmology Retina/Vitreous Panel (2015). Age-related macular degeneration. Preferred Practice Pattern Guidelines. San Francisco: American Academy of Ophthalmology. http://www.aao.org/preferred-practice-pattern/age-related-macular-degeneration-ppp-2015. Accessed April 30, 2015.Christen WG, et al. (2012). Vitamins E and C and medical record-confirmed age-related macular degeneration in a randomized trial of male physicians. Ophthalmology, 119(8): 1642-1649.Other Works ConsultedDrugs for some common eye disorders (2012). Treatment Guidelines From The Medical Letter, 10(123): 79-86.
ByHealthwise StaffPrimary Medical ReviewerKathleen Romito, MD - Family MedicineAdam Husney, MD - Family MedicineSpecialist Medical ReviewerChristopher J. Rudnisky, MD, MPH, FRCSC - Ophthalmology
Current as ofMarch 3, 2017
Current as of:
March 3, 2017
Kathleen Romito, MD - Family Medicine & Adam Husney, MD - Family Medicine & Christopher J. Rudnisky, MD, MPH, FRCSC - Ophthalmology
To learn more about Healthwise, visit Healthwise.org.
© 1995-2017 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Last modified on: 8 September 2017